Monthly medicines update
Summary of new marketing authorisations and changes to existing authorisations that relate to the safe use of the product
A rolling 6 month summary with the most recent one first.
Our Product Information Database (PID) is your primary resource for the most current information about all veterinary medicines authorised in Great Britain and Northern Ireland. As product details change we update the Summary of Product Characteristics (SPC) and label text there. Please note there may be a delay before formal documentation is available for some Northern Ireland products.
It may take up to 12 months for changes to appear on marketed packaging.
Products are authorised separately in Great Britain and Northern Ireland although authorisations may be aligned if they are the same product held by the same authorisation holder. This may mean that products are authorised or changed on different timescales in each territory.
Also find here a list of specific Pregnancy Warnings which we update quarterly.
July 2025
New Authorisations
-
BioEquin F Suspension for Injection for Horses
Active substance: Equine influenza virus
Territory / Distribution category: NI POM-V
Authorisation holder: Bioveta, a.s.
-
BioEquin FT Suspension for Injection for Horses
Active substance: Clostridium tetani, Equine influenza virus
Territory / Distribution category: NI POM-V
Authorisation holder: Bioveta, a.s. Limited
-
Nobilis Multriva Gm+REOm Emulsion for Injection for Chickens
Active substance: Infectious bursal disease virus; Avian reovirus
Territory / Distribution category: NI POM-V
Authorisation holder: Intervet International B.V.
SPC Available from EU Union Product Database
-
Nobilis Multriva IBm+ND+Gm+REOm+EDS Emulsion for Injection for Chickens
Active substance: Newcastle disease virus, Infectious bursal disease virus, Avian reovirus, Egg drop syndrome virus
Territory / Distribution category: NI POM-V
Authorisation holder: Intervet International B.V.
SPC available on the EU Union Product Database
-
Sulfequine 333 mg/g + 67 mg/g Oral Paste for Horses
Active substance: Sulfadiazine, Trimethoprim
Territory / Distribution category: NI POM-V
Authorisation holder: CP Pharma Handelsgesellschaft mbH
-
Ventimaxx 25 Microgram/ml Oral Solution for Horses
Active substance: Clenbuterol hydrochloride
Territory / Distribution category: NI POM-V
Authorisation holder: Alfasan Nederland B.V.
-
VeteCorH 1000 IU/ml Lyophilisate and Solvent for Solution for Injection for Cattle, Horses, Sheep, Goats, Pigs, Cats and Dogs
Active substance: Chorionic Gonadotrophin
Territory / Distribution category: NI, POM-V
Authorisation holder: Laboratorios Calier, S.A.
-
Daxocox 140 mg Tablets for Dogs; Daxocox 200 mg Tablets for Dogs
Active substance: Enflicoxib
Territory / Distribution category: GB, POM-V
Authorisation holder: Ecuphar NV
-
Lozenord 5 mg/ml Solution for Injection for Dogs and Cats
Active substance: Meloxicam
Territory / Distribution category: GB, POM-V
Authorisation holder: Accord Healthcare B.V
-
Meloxicam-Boehringer 0.5 mg/ml Oral Suspension for Cats and Guinea Pigs; Meloxicam-Boehringer 1.5 mg/ml Oral Suspension for Dogs
Active substance: Meloxicam
Territory / Distribution category: GB, POM-V
Authorisation holder: Boehringer Ingelheim Animal Health UK Limited
Link to SPC Cats and Guinea Pigs
-
Numelvi 4.8 mg Tablets for Dogs; Numelvi 7.2 mg Tablets for Dogs; Numelvi 21.6 mg Tablets for Dogs; Numelvi 31.6 mg Tablets for Dogs
Active substance: Atinvicitinib
Territory / Distribution category: NI, POM-V
Authorisation holder: Intervet International BV
SPCs available from EU Union Product Database
-
Omeprazole TriviumVet 10 mg Gastro-resistant Capsules for Dogs
Active substance: Omeprazole
Territory / Distribution category: NI POM-V
Authorisation holder: TriviumVet DAC
SPC available from EU Union Product Database
-
Prevexto 1.25 g + 0.56 g, Medicated Collar for Cats; Prevexto 1.25 g + 0.56 g, Medicated Collar for Dogs up to 8 kg; Prevexto 4.50 g + 2.03 g, Medicated Collar for Dogs over 8 kg
Active substance: Imidacloprid, Flumethrin
Territory / Distribution category: NI NFA-VPS
Authorisation holder: VIRBAC
Link to SPC 1.25g + 0.56g Cats
Link to SPC 1.25g + 0.56g Dogs
Link to SPC 4.50g +0.56g Dogs over 8kg
-
Zenrelia 4.8 mg Film-coated Tablets for Dogs; Zenrelia 6.4 mg Film-coated Tablets for Dogs; Zenrelia 8.5 mg Film-coated Tablets for Dogs; Zenrelia 15 mg Film-coated Tablets for Dogs
Active substance: Ilunocitinib
Territory / Distribution category: NI POM-V
Authorisation holder: Elanco GmbH
SPCs available from EU Union Product Database
Variations - food producing species
-
DIVENCE PENTA Lyophilisate and Solvent for Emulsion for Injection [Cattle]
Active substance: Bovine parainfluenza virus 3, Bovine respiratory syncytial virus,
E2 recombinant protein, Infectious bovine rhinotracheitis virus
Territory / Distribution category: NI POM-V
Authorisation holder: Laboratorios Hipra SA
Change Category: Target species use; adverse reactions
Summary of change:
Section 4.9: Clarification of the temperature of use (15 °C – 25 °C) to ensure the correct handling of the veterinary medicinal product.
Section 3.6: Addition with a frequency of uncommon adverse events related to a temporary mild reduction in milk production, feed intake and activity.
SPC available from EU Union Product Database
-
Unistrain PRRS Lyophilisate and Solvent for Suspension for Injection for Pigs
Active substance: Porcine respiratory and reproductive syndrome virus
Territory / Distribution category: NI POM-V
Authorisation holder: Laboratorios Hipra SA
Change Category: Target Species Use
Summary of change:
Sections 3.2 and 3.9: Update to reduce the minimum age of vaccination of pigs from 4 weeks to 3 weeks.
-
Vey Tosal 100 mg/ml + 0.05 mg/ml Solution for Injection for Horses, Cattle and Dogs
Active substance: Butafosfan, Cyanocobalamin
Territory / Distribution catgory: NI POM-V
Authorisation holder: Veyx-Pharma GmbH
Change category: Target Species Use
Summary of change:
Section 3.1: Removal of cats as a target species.
Section 3.2: updated indications:
All target species:
- Supportive treatment and prevention of hypophosphatemia and/or cyanocobalamin (vitamin B12) deficiency.
Cattle:
- Supportive treatment to restore rumination following surgical treatment of displaced abomasum associated with secondary ketosis.
- Complementary treatment of parturient paresis in addition to Ca/Mg therapy.
- Prevention of ketosis development, if administered before calving.
Horses:
- Adjunctive therapy in horses suffering from muscular exhaustion.
Variations - Companion animal species
-
Bravecto 112.5 mg / 250 mg / 500 mg spot-on solution for cats
Active substance: Fluralaner
Territory / Distribution category: NI POM-V
Authorisation holder: Intervet International B.V.
Change Category: Adverse Reactions
Summary of change:
Section 3.6: Addition of ataxia and pruritus with a frequency of very rare (<1 animal/10,000 animals treated, including isolated reports).
SPCs available from EU Union Product Database
-
Bravecto Chewable Tablets for Dogs [Range]; Bravecto spot-on solution for dogs [Range]
Active substance: Fluralaner
Territory / Distribution category: NI POM-V
Authorisation holder: Intervet International B.V
Change Category: Adverse Reactions
Summary of change:
Section 3.6: Addition of diarrhoea with a frequency of common (1 to 10 animals / 100 animals treated), and pruritus with a frequency of very rare (<1 animal/10,000 animals treated, including isolated reports).
SPCs available from EU Union Product Database
-
Cazitel Plus XL Tablets for Dogs
Active substance: Febantel, Praziquantel,
Pyrantel Embonate
Territory / Distribution category: NI POM-V
Authorisation holder: Laboratorios Hipra SA
Change Category: Adverse Reactions
Summary of change:
Section 3.6: Addition of lethargy, anorexia, and hyperactivity with a frequency of very rare (<1 animal/10,000 animals treated, including isolated reports).
-
Eurican DHPPi [Dogs]
Active substance: Canine adenovirus, Canine distemper virus, Canine parainfluenza virus, Canine parvovirus
Territory / Distribution category: UK POM-V
Authorisation holder: Boehringer Ingelheim Animal Health UK Limited
Change Category: Interactions and Overdose
Summary of change:
Section 4.8: To add the compatibility claim for Eurican DHPPi with Eurican L4.
-
NexGard Combo spot-on solution for cats <2.5 kg; NexGard Combo spot-on solution for cats 2.5-7.5 kg
Active substance: Eprinomectin, Esafoxolaner, Praziquantel
Territory / Distribution category: NI POM-V
Authorisation holder: Boehringer Ingelheim Vetmedica GmbH
Change Category: Target Species Use
Summary of change:
Section 3.2: Addition of a new indication: for the treatment of infections with eye worms (Thelazia callipaeda).
Modification of an indication for immediate tick killing activity against Ixodes hexagonus
Corresponding changes have been made to sections 3.4, 3.9, and 4.3 of the SPCs.
SPCs available from EU Union Product Database
-
Nexgard Spectra Chewable Tablets for Dogs [Range]
Active substance: Afoxolaner, Milbemycin Oxime (A3 and A4)
Territory / Distribution category: NI POM-V
Authorisation holder: Boehringer Ingelheim Vetmedica GmbH
Change Category: Target Species Use
Summary of change:
Section 3.2: Addition of two new indications:
For reduction of the risk of infection with Dipylidium caninum via transmission by Ctenocephalides felis for 30 days.
For reduction of the risk of infection with Babesia canis canis via transmission by Dermacentor reticulatus for 28 days.
The effects are indirect due to the activity of the veterinary medicinal product against the vectors.
Corresponding changes have been made to sections 3.4, 3.9, and 4.3 of the SPCs.
SPC available from EU Union Product Database
-
Nobivac L4 Suspension for Injection for Dogs
Active substance: Leptospira australis, Leptospira canicola, Leptospira grippotyphosa, Leptospira icterohaemorrhagiae
Territory / Distribution category: NI POM-V
Authorisation holder: Intervet International B.V.
Change Category: Target Species Use; Interactions and Overdose
Summary of change:
Section 3.2: Addition of a new therapeutic indication for 2 new Leptospira serovars, and existing Leptospira serovars.
Section 3.8: Addition of associated non-mixed use with Nobivac Rabies vaccine.
SPC available from EU Union Product Database
-
Nobivac LoVo L4 Suspension for Injection for Dogs
Active substance: Leptospira interrogans serogroup Australis, Leptospira interrogans serogroup Canicola, Leptospira interrogans serogroup Icterohaemorrhagiae, Leptospira kirschneri serogroup Grippotyphosa
Territory / Distribution category: NI POM-V
Authorisation holder: Intervet International B.V.
Change Category: Target Species Use; Interactions and Overdose
Summary of change:
Section 3.2: Addition of a new therapeutic indication for 2 new Leptospira serovars, and existing Leptospira serovars.
Section 3.8: Addition of associated non-mixed use with Nobivac Rabies vaccine.
SPC available from EU Union Product Database
-
Prazitel Plus Tablets for Dogs
Active substance: Febantel, Praziquantel, Pyrantel
Territory / Distribution category: GB NFA-VPS
Authorisation holder: Chanelle Pharmaceuticals Manufacturing Ltd
Change Category: Adverse Reactions
Summary of change:
Section 3.6: Addition of lethargy, anorexia, and hyperactivity with a frequency of very rare (<1 animal/10,000 animals treated, including isolated reports).
-
Quantilex Plus XL Tablets for Dogs
Active substance: Febantel, Praziquantel, Pyrantel Embonate
Territory / Distribution category: GB NFA-VPS
Authorisation holder: Chanelle Pharmaceuticals Manufacturing Ltd
Change Category: Adverse Reactions
Summary of change:
Section 3.6: Addition of lethargy, anorexia, and hyperactivity with a frequency of very rare (<1 animal/10,000 animals treated, including isolated reports).
-
Seresto Flea and Tick Control 1.25 g + 0.56 g, Collar for Cats; Seresto Flea and Tick Control 1.25 g + 0.56 g, Collar for Small Dogs ≤ 8 kg; Seresto Flea and Tick Control 4.50 g + 2.03 g, Collar for Large Dogs > 8 kg
Active substance: Flumethrin, Imidacloprid
Territory / Distribution category: UK NFA-VPS
Authorisation holder: Elanco Europe Ltd
Change Category: Adverse Reactions
Summary of change:
Section 3.6: Addition of application site reaction (haemorrhage and scratching), behavioural disorder (vocalisation) and lethargy with a frequency of rare (1 to 10 animals / 10000 animals treated).
-
Simparica Trio Chewable Tablets for Dogs [Range]
Active substance: Moxidectin, Pyrantel, Sarolaner
Territory / Distribution category: GB POM-V
Authorisation holder: Zoetis UK Limited
Change Category: Target Species Use
Summary of change:
Section 3.2: Added for the treatment of Angiostrongylus vasorum.
Section 3.9: Treatment of angiostrongylosis (caused by Angiostrongylus vasorum):
A single dose should be administered. A further veterinary examination 30 days after treatment is recommended as some animals may require a second treatment. A further assessment should then be carried out following the second treatment. Continued monitoring should be performed as appropriate for each case.
-
Vey Tosal 100 mg/ml + 0.05 mg/ml Solution for Injection for Horses, Cattle and Dogs
Active substance: Butafosfan
Cyanocobalamin
Territory / Distribution category: NI POM-V
Authorisation holder: Veyx-Pharma GmbH
Change Category: Target Species Use
Summary of change:
Section 3.1: Removal of cats as a target species.
Section 3.2: updated indications for all target species: Supportive treatment and prevention of hypophosphatemia and/or cyanocobalamin (vitamin B12) deficiency.
June 2025
New Authorisations
-
Avishield IB QX Lyophilisate for Oculonasal Suspension/use in Drinking Water for Chickens
Active substance: Avian infectious bronchitis virus
Territory / Distribution category: NI POM-V
Authorisation holder: Genera Inc.
-
Innovax-ND-H5 Concentrate and Solvent for Suspension for Injection for Chickens
Active substance: Turkey herpesvirus
Territory / Distribution category: GB POM-V
Authorisation holder: MSD Animal Health UK Limited
-
Lincoral-S 222 mg/g + 444.7 mg/g Powder for Use in Drinking Water for Pigs and Chickens
Active substance: Lincomycin Hydrochloride, Spectinomycin Sulphate
Territory / Distribution category: GB POM-V
Authorisation holder: Huvepharma NV
-
Nobilis Multriva IBm+ND
Active substance: Infectious bronchitis virus, Infectious bronchitis virus, Newcastle disease virus
Territory / Distribution category: NI POM-V
Authorisation holder: Intervet International B.V.
SPC available on the EU Union Product Database
-
Ovimel 18 mg Implantation Tablets for Sheep
Active substance: Melatonin
Territory / Distribution category: GB & NI POM-VPS
Authorisation holder: Vetpharma Animal Health, S.L
-
Syvazul BTV 3 Suspension for Injection for Sheep and Cattle
Active substance: Bluetongue virus
Territory / Distribution category: GB POM-V
Authorisation holder: Laboratorios SYVA S.A.U
-
Vectormune HVT-AIV Concentrate and Solvent for Suspension for Injection for Chickens
Active substance: Cell-associated live recombinant turkey herpesvirus
Territory / Distribution category: GB, POM-V
Authorisation holder: Ceva Animal Health Ltd
-
Beaphar WORMclear PLUS 30 mg/7.5 mg Spot-on Solution for Small Cats; Beaphar WORMclear PLUS 60 mg/15 mg Spot-on Solution for Medium Cats; Beaphar WORMclear PLUS 96 mg/24 mg Spot-on Solution for Large Cats
Active substance: Praziquantel, Emodepside
Territory / Distribution category: GB, POM-V
Authorisation holder: KRKA, d.d., Novo mesto
-
Daxocox 140 mg Tablets for Dogs; Daxocox 200 mg Tablets for Dogs
Active substance: Enflicoxib
Territory / Distribution category: GB, POM-V
Authorisation holder: Ecuphar NV
-
Elmaro 10 mg/ml Solution for Injection for Dogs and Cats
Active substance: Maropitant
Territory / Distribution category: GB, POM-V
Authorisation holder: Elanco GmbH
-
Meloxicam-Boehringer 0.5 mg/ml Oral Suspension for Cats and Guinea Pigs; Meloxicam-Boehringer 1.5 mg/ml Oral Suspension for Dogs
Active substance: Meloxicam
Territory / Distribution category: GB, POM-V
Authorisation holder: Boehringer Ingelheim Animal Health UK Limited
Link to SPC Cats and Guinea Pigs
-
Novospot Worming Solution 30 mg/7.5 mg Spot-on Solution for Small Cats; Novospot Worming Solution 60 mg/15 mg Spot-on Solution for Medium Cats; Novospot Worming Solution 96 mg/24 mg Spot-on Solution for Large Cats
Active substance: Praziquantel, Emodepside
Territory / Distribution category: GB, POM-V
Authorisation holder: KRKA, d.d., Novo mesto
-
Pet Shield Worm Screen 30 mg/7.5 mg Spot-on Solution for Small Cats; Pet Shield Worm Screen 60 mg/15 mg Spot-on Solution for Medium Cats; Pet Shield Worm Screen 96 mg/24 mg Spot-on Solution for Large Cats
Active substance: Praziquantel, Emodepside
Territory / Distribution category: GB, POM-V
Authorisation holder: KRKA, d.d., Novo mesto
Variations - food producing species
-
Bovilis Rotavec Corona Emulsion for Injection for Cattle
Active substance: Bovine coronavirus, Bovine rotavirus, Escherichia coli
Territory / Distribution category: GB POM-VPS
Authorisation holder: MSD Animal Health UK Limited
Change Category: Interactions & Overdose
Summary of change:
SPC section 3.8: Updated to allow the associated non-mixed use of Bovilis Rotavec Corona and Bovilis Cryptium.
SPC section 3.9: Added subcutaneous route of administration.
-
Porcilis PRRS Lyophilisate and Solvent for Suspension for Injection for Pigs
Active substance: Porcine respiratory and reproductive syndrome virus
Territory / Distribution category: NI POM-V
Authorisation holder: Intervet International B.V.
Change Category: Interactions & Overdose
Summary of change:
SPC section 3.8: Product information of Porcilis PRRS updated to include associated use combinations with Porcilis PCV M Hyo ID.
-
Porcilis Lawsonia ID Lyophilisate and Solvent for Emulsion for Injection for Pigs
Active substance: Lawsonia intracellularis
Territory / Distribution category: NI POM-V
Authorisation holder: Intervet International B.V.
Change category:
Summary of change:
SPC section 3.8: Product information of Porcilis Lawsonia ID updated to include associated use combinations with Porcilis PCV M Hyo ID.
-
DIVENCE PENTA Lyophilisate and Solvent for Emulsion for Injection (Cattle)
Active substance: Bovine parainfluenza virus 3, Bovine respiratory syncytial virus, E2 recombinant protein, Infectious bovine rhinotracheitis virus
Territory / Distribution category: GB POM-V
Authorisation holder: Laboratorios Hipra SA
Change Category: Adverse reactions, Target species use
Summary of change:
SPC section 3.6: A temporary mild reduction in milk production, feed intake and activity may uncommonly be observed in dairy cows mostly after the first dose (1 to 10 animals / 1,000 animals treated).
SPC section 4.9: Allow the vaccine to reach a temperature of +15 to+ 25 °C before administration.
-
DiarrVac RCE Emulsion for Injection for Cattle; Bovigen Scour Emulsion for Injection for Cattle
Active substance: Bovine coronavirus, Bovine rotavirus, Escherichia coli
Territory / Distribution category: NI POM-VPS
Authorisation holder: Forte Healthcare Limited
Change Category: Target species use
Summary of change:
SPC sections 2 and 4.2: Update to indicate that the EC/17 vaccine strain stimulates an antibody response to F41, in addition to F5.
Variations - Companion animal species
-
Clavaseptin 50 mg / 62.5 mg Palatable Tablets for Dogs and Cats Clavaseptin 250 mg / 500 mg / 750 mg Palatable Tablets for Dogs
Active substance: Amoxicillin, Clavulanic Acid
Territory / Distribution category: NI POM-V
Authorisation holder: Vetoquinol UK Ltd
Change Category: Target species use
Summary of change:
SPC section 3.2:
In dogs: treatment of infections caused by bacteria susceptible to amoxicillin in combination with clavulanic acid (including beta-lactamase producing strains), in particular:
• Skin infections (including deep and superficial pyodermas, wounds, abscesses) caused by Staphylococcus spp., Streptococcus spp., and Pasteurella spp.
• Respiratory tract infections (sinusitis, rhino-tracheitis, bronchopneumonia) caused by Staphylococcus spp., and E. coli.
• Infections of the oral cavity (mucous membranes) caused by Streptococcus spp., and Pasteurella spp.
• Urinary tract infections (nephritis, cystitis) caused by E. coli, Klebsiella spp. and Proteus mirabilis.
• Digestive tract infections, especially gastroenteritis caused by E. coli.
In cats: treatment of infections caused by bacteria susceptible to amoxicillin in combination with clavulanic acid (including beta-lactamase producing strains), in particular:
• Skin infections (including deep and superficial pyodermas, wounds, abscesses) caused by Staphylococcus spp, Streptococcus spp. and Pasteurella spp.
• Respiratory tract infections (sinusitis, rhino-tracheitis, bronchopneumonia) caused by Staphylococcus spp. and E. coli.
• Infections of the oral cavity (mucous membranes) caused by Streptococcus spp., and Pasteurella spp.
• Urinary tract infections (nephritis, cystitis) caused by E. coli, Pasteurella spp., Klebsiella spp. and Proteus mirabilis.
• Digestive tract infections, especially gastroenteritis caused by E. coli.
Link to SPC 50mg dogs and cats
Link to SPC 62.5mg dogs and cats
-
Credelio 12 mg Chewable Tablets for Cats (0.5–2.0 kg); Credelio 48 mg Chewable Tablets for Cats (>2.0–8.0kg)
Active substance: Lotilaner
Territory / Distribution category: GB POM-V
Authorisation holder: Elanco GmbH
Change Category: Adverse reactions
Summary of change:
SPC section 3.6: Added the adverse events anorexia, lethargy, tachypnoea, ataxia, muscle tremor, hyperactivity and pruritus with a frequency of very rare (<1 animal/10,000 animals treated, including isolated reports).
-
Simparica Trio Chewable Tablets for Dogs (Range)
Active substance: Moxidectin, Pyrantel, Sarolaner
Territory / Distribution category: NI POM-V
Authorisation holder: Zoetis Belgium
Change Category: Target species use
Summary of change:
SPC section 3.2: Addition of indication for the treatment of angiostrongylosis (Angiostrongylus vasorum) and associated dosing advice.
SPCs available from EU Union Product Database
May 2025
New Authorisations
-
Icthiovac Erm Concentrate for dip suspension for Atlantic salmon
Active substance: Yersinia ruckeri
Territory / Distribution category: NI POM-V
Authorisation holder: Laboratorios Hipra SA
SPC available from EU Union Product Database
-
Nobilis Multriva IBm+ND+EDS Emulsion for Injection for Chickens
Active substance: Infectious bronchitis virus, Newcastle disease virus, Egg drop syndrome virus
Territory / Distribution category: NI POM-V
Authorisation holder: Intervet International BV
SPC available from EU Union Product Database
-
Poulvac Poulinac ND+IB M41+EDS Emulsion for Injection for Chickens
Active substance: Newcastle disease virus, Infectious bronchitis virus, Egg drop syndrome virus,
Territory / Distribution category: GB POM-V
Authorisation holder: Laboratorios Karizoo S.A
-
Amlodicor 1.25 mg Chewable Tablets for Cats
Active substance: Amlodipine
Territory / Distribution category: GB POM-V
Authorisation holder: Ceva Animal Health Ltd
-
Amocard 1.25 mg Chewable Tablets for Cats
Active substance: Amlodipine
Territory / Distribution category: GB POM-V
Authorisation holder: Accord Healthcare B.V
-
Prazemo Spot-On Worming Solution 30 mg/7.5 mg Spot-on Solution for Small Cats;Prazemo Spot-On Worming Solution 60 mg/15 mg Spot-on Solution for Medium Cats; Prazemo Spot-On Worming Solution 96 mg/24 mg Spot-on Solution for Large Cats
Active substance: Emodepside, Praziquantel
Territory / Distribution category: GB & NI POM-V
Authorisation holder: KRKA, d.d., Novo mesto
-
Prazendo 50 mg Tablets for Dogs
Active substance: Praziquantel
Territory / Distribution category: GB, AVM-GSL
Authorisation holder: Ashish Life Science Holding B.V.
-
Praziquantel/Emodepside Krka Worming Spot-on Solution 30 mg/7.5 mg for Small Cats; Praziquantel/Emodepside Krka Worming Spot-on Solution 60 mg/15 mg for Medium Cats; Praziquantel/Emodepside Krka Worming Spot-on Solution 96 mg/24 mg for Large Cats
Active substance: Emodepside, Praziquantel
Territory / Distribution category: GB & NI, POM-V
Authorisation holder: KRKA, d.d., Novo mesto
Variations - food producing species
-
Bovalto Respi Intranasal, Nasal Spray, Lyophilisate and Solvent for Suspension (Cattle)
Active substance: Bovine respiratory syncytial virus, Bovine parainfluenza virus 3
Territory / Distribution category: NI POM-V
Authorisation holder: Boehringer Ingelheim Animal Health UK Limited
Change Category: Indications for use
Summary of change:
Section 3.9: Addition of further information to the user regarding the reconstitution of the 10-dose presentation to avoid any misuse in the field.
-
DIVENCE IBR MARKER LIVE Lyophilisate and Solvent for Emulsion for Injection (Cattle)
Active substance: Infectious bovine rhinotracheitis virus
Territory / Distribution category: GB POM-V
Authorisation holder: Laboratorios Hipra SA
Change Category: Indications for use
Summary of change:
Section 3.9: DIVENCE IBR MARKER LIVE vaccine may be used for subsequent re-vaccinations after vaccination with DIVENCE TRI vaccine if there is no further need for protection against BRSV and PI-3, where available.
-
Nuflor 300 mg/ml Solution for Injection for Cattle and Sheep
Active substance: Florfenicol
Territory / Distribution category: GB & NI POM-V
Authorisation holder: MSD Animal Health UK Limited
Change category: Contraindications, special warning
Summary of change:
Section 5.5: The veterinary medicinal product should not enter water courses as florfenicol may be dangerous for aquatic organisms.
Variations - Companion animal species
-
Alizin 30 mg/ml Solution for Injection (Dogs)
Active substance: Aglepristone
Territory / Distribution category: NI POM-V
Authorisation holder: Virbac
Change Category: Contraindications, special warnings; Adverse reactions
Summary of change:
Section 3.5: Bitches that remain pregnant despite treatment should be monitored, as viability of the puppies may be compromised and serious complications such as dystocia and uterine rupture could result from abortion failure.
Section 3.6: Associated lack of efficacy adverse event included.
-
Ataxxa Spot-on Solution for Dogs (Range)
Active substance: Imidacloprid; Permethrin (Cis:Trans 40:60)
Territory / Distribution category: NI POM-V
Authorisation holder: KRKA, d.d., Novo mesto
Change Category: Contradications, Special warnings
Summary of change:
Section 3.5: Added for the 2000 mg/400 mg pipette size only:
The product should not be administered by pregnant women and women suspected of being pregnant. Gloves should be worn by women of childbearing age when handling the veterinary medicinal product.
Section 3.7: Added warnings regarding foetotoxic effects identified in rabbits and rats of the excipient N methyl pyrrolidone.
-
Lotilaner Elanco Chewable Tablets for Dogs (Range); Lotilaner Elanco Chewable Tablets for Cats (Range)
Active substance: Lotilaner
Territory / Distribution category: NI NFA-VPS
Authorisation holder: Elanco GmbH
Change Category: Change in distribution category
Summary of change:
Change in distribution category from POM-V to NFA-VPS with the removal of indications regarding flea allergy dermatitis (FAD) and demodicosis to reflect the change to a non prescription status.
SPCs available from EU Union Product Database
April 2025
New Authorisations
-
Bluevac-3 Suspension for Injection for Sheep and Cattle
Active substance: Bluetongue Virus
Territory / Distribution category: GB &NI POM-V
Authorisation holder: CZ Veterinaria S.A.
NI SPC available from EU Union
-
Bultavo 3 Suspension for Injection for Sheep and Cattle
Active substance: Bluetongue virus
Territory / Distribution category: GB & NI POM-V
Authorisation holder: Boehringer Ingelheim Animal Health UK Limited
-
Diclacare 2.5 mg/ml Oral Suspension for Lambs and Calves
Active substance: Diclazuril
Territory / Distribution category: NI POM-V
Authorisation holder: Laboratorios Karizoo S.A
-
Triclacert Duo 50 mg/ml & 1 mg/ml Oral Suspension for Sheep
Active substance: Triclabendazole, Ivermectin
Territory / Distribution category: GB POM-V
Authorisation holder: EU Pharmaceuticals Ltd
-
Censutrim 200 mg/ml + 40 mg/ml Solution for Injection for Cattle, Pigs, Horses, Dogs and Cats
Active substance: Sulfadiazine, Trimethoprim
Territory / Distribution category: GB POM-V
Authorisation holder: DUGV (UK) Limited
-
Benamix 6.25 mg/g Premix for Medicated Feeding Stuff for Cats
Active substance: Benazepril
Territory / Distribution category: GB & NI POM-V
Authorisation holder: VIRBAC
-
Bravecto TriUNO Chewable Tablets for Dogs [Range]
Active substance: Fluralaner, Moxidectin, Pyrantel
Territory / Distribution category: GB & NI POM-V
Authorisation holder: MSD Animal Health UK Limited
-
Elmaro 10 mg/ml Solution for Injection for Dogs and Cats
Active substance: Maropitant
Territory / Distribution category: NI POM-V
Authorisation holder: Elanco GmbH
SPC available from EU Union Product Database
-
Ezi-Wormer Film-coated Tablets for Cats 16/40 mg (Milbemycin/Praziquantel)
Active substance: Milbemycin Oxime (A3 and A4), Praziquantel
Territory / Distribution category: GB POM-V
Authorisation holder: C&H Generics Ltd
-
Prevestrus Vet Film-Coated Tablets for Dogs [Range]
Active substance: Finrozole
Territory / Distribution category: NI POM-V
Authorisation holder: Vetcare Oy
Link to SPC 25mg
Link to SPC 50mg
Link to SPC 100mg
-
Vetmedin 1.5 mg/ml Oral Solution for Dogs
Active substance: Pimobendan
Territory / Distribution category: NI POM-V
Authorisation holder: Boehringer Ingelheim Animal Health UK Limited
-
Wormax Film-coated Tablets for Cats 16/40 mg
Active substance: Milbemycin Oxime (A3 and A4), Praziquantel
Territory / Distribution category: GB POM-V
Authorisation holder: C&H Generics Ltd
-
Wormit Film-coated Tablets for Cats 16/40 mg
Active substance: Milbemycin Oxime (A3 and A4), Praziquantel
Territory / Distribution category: GB POM-V
Authorisation holder: C&H Generics Ltd
Variations - food producing species
-
Medesedan 10 mg/ml Solution for Injection for Horses and Cattle
Active substance: Detomidine Hydrochloride
Territory / Distribution category: GB & NI POM-V
Authorisation holder: CP Pharma Handelsgesellschaft mbH
Summary of change:
Multiple extensive updates have been made in relation to the SPC sections; 3.3 Contraindications, 3.5 Special precautions for use; 3.6 Adverse events, 3.7 Fertility, use during pregnancy and lactation, 3.9 Administration in combination with other sedatives and anaesthetics and 3.10 Overdose.
-
Detogesic 10 mg/ml Solution for Injection for Horses
Active substance: Detomidine Hydrochloride
Territory / Distribution category: NI POM-V
Authorisation holder: Vetcare Limited
Summary of change:
Multiple extensive updates have been made in relation to the SPC sections; 3.2 Indications, 3.3 Contraindications, 3.5 Special precautions for use, 3.6 Adverse events, 3.7 Fertility, use during pregnancy and lactation, 3.8 Interactions with other medicinal products, 3.9 Administration routes and dosage, 3.10 Overdose and 4.2 and 4.3 Pharmacology.
-
Vigophos 100 mg / ml + 0.05 mg / ml Solution for Injection for Cattle, Horses and Dogs
Active substance: Butafosfan, Cyanocobalamin
Territory / Distribution category: GB & NI POM-V
Authorisation holder: Livisto Int'l, S.L.
Change category: Target species
Summary of change:
The veterinary medicinal product is now authorised for use in horses for supportive treatment and prevention of hypophosphataemia and/or cyanocobalamin (vitamin B12) deficiency, and as an adjunctive therapy in horses suffering from muscular exhaustion. Extensive associated changes have been made to multiple sections of the SPC due to the addition of this new target species.
See under Companion animals listing for changes relevant for use in dogs.
-
Zermex 100 mg/ml LA Solution for Injection for Cattle
Active substance: Moxidectin
Territory / Distribution category: GB & NI POM-VPS
Authorisation holder: Zoetis UK Limited
Change category: Contraindications, Special warnings; Adverse reactions; Target species use.
Summary of change:
Sections 4.4 and 4.5 have been updated to provide further warnings and precautions to advise on safe and effective use.
Section 4.6 has been updated to indicate that on very rare occasions, hypersensitivity reactions and/or neurological disorders (such as collapse, convulsion, paralysis, and blindness) may occur. Severe reactions may be fatal.
Section 4.9 has been updated to provide further general information regarding dosing.
-
Zermex 20 mg/ml LA Solution for Injection for Sheep
Active substance: Moxidectin
Territory / Distribution category: GB & NI POM-VPS
Authorisation holder: Zoetis UK Limited
Change category: Contraindications, Special warnings; Adverse reactions;
Summary of change:
Section 4.4 has been updated to provide further warnings relating to effective use.
Section 4.6 has been updated to indicate that on very rare occasions, neurological disorders such as collapse, convulsion, and paralysis may occur. Severe reactions may be fatal.
Variations - Companion animal species
-
Osurnia Ear Gel for Dogs
Active substance: Terbinafine, Florfenicol, Betamethasone acetate
Territory / Distribution category: GB & NI POM-V
Authorisation holder: Dechra Limited (GB) Dechra Regulatory B.V. (NI)
Change Category: Contraindications, Special warnings; Adverse reactions
Summary of change:
Information relating to the occurrence of eye disorders, despite no direct ocular contact, has been removed from section 4.5. Instead, section 4.6 has been updated to indicate that in very rare cases, eye disorders such as neurogenic keratoconjunctivitis sicca, keratoconjunctivitis sicca, corneal ulcer, blepharospasm, eye redness and ocular discharge have been reported in treated dogs. Additionally, ataxia, internal ear disorders (mainly head tilt), facial paralysis and nystagmus have been reported in very rare cases.
NI SPC Available from EU Union Product Database
-
StromEase 25 mg/ml Eye Drops, Solution for Dogs and Cats
Active substance: Acetylcysteine
Territory / Distribution category: GB & NI POM-V
Authorisation holder: DOMES PHARMA
Change Category: Adverse events
Summary of change:
Section 4.6 has been amended to clarify that irritation or inflammation of the eye and/or its adnexa have been reported in very rare cases, especially blinking of the eyelids or even closure of the eye, eye redness or conjunctival oedema, particularly in dogs.
-
Vigophos 100 mg / ml + 0.05 mg / ml Solution for Injection for Cattle, Horses and Dogs
Active substance: Acetylcysteine
Territory / Distribution category: GB & NI POM-V
Authorisation holder: DOMES PHARMA
Change Category: Target species
Summary of change:
The veterinary medicinal product is now authorised for use in dogs for supportive treatment and prevention of hypophosphataemia and/or cyanocobalamin (vitamin B12) deficiency. Extensive associated changes have been made to multiple sections of the SPC due to the addition of this new target species.
March 2025
New Authorisations
-
Censutrim 200 mg/ml + 40 mg/ml Solution for Injection for Cattle, Pigs, Horses, Dogs and Cats
Active substance: Sulfadiazine, Trimethoprim
Territory / Distribution category: NI, POM-V
Authorisation holder: DUGV (UK) Limited
-
Cevac Salmune ETI K Suspension for Injection for Chickens
Active substance: Salmonella enterica subsp. enterica
Territory / Distribution category: GB POM-V
Authorisation holder: Cevac Salmune ETI K
-
Intramar Lacto 200mg + 50mg + 10mg Intramammary Suspension for Cattle
Active substance: Amoxicillin, Clavulanic acid, Prednisolone
Territory / Distribution category: GB & NI POM-V
Authorisation holder: Bioveta, a.s.
-
Mastic Seal 2.6 g Intramammary Suspension for Cattle
Active substance: Bismuth subnitrate
Territory / Distribution category: GB POM-V
Authorisation holder: Bioveta, a.s.
-
Taurador 10 mg/ml Solution for Injection for Cattle & Sheep
Active substance: Doramectin
Territory / Distribution category: GB & NI POM-VPS
Authorisation holder: Norbrook Laboratories Limited
-
ArthriCox 57 mg Chewable Tablets for Dogs; ArthriCox 227 mg Chewable Tablets for Dogs
Active substance: Firocoxib
Territory / Distribution category: GB POM-V
Authorisation holder: Norbrook Laboratories Limited
-
ButorVet 10 mg/ml Solution for Injection for Horses, Dogs and Cats
Active substance: Butorphanol
Territory / Distribution category: GB & NI POM-V
Authorisation holder: C&H Generics Ltd
-
OsteoCox 57 mg Chewable Tablets for Dogs; OsteoCox 227 mg Chewable Tablets for Dogs
Active substance: Firocoxib
Territory / Distribution category: GB & NI POM-V
Authorisation holder: Chanelle Pharmaceuticals Manufacturing Ltd
-
Vetmedin 1.5 mg/ml Oral Solution for Dogs
Active substance: Pimobendan
Territory / Distribution category: GB POM-V
Authorisation holder: Boehringer Ingelheim Animal Health UK Limited
Variations - food producing species
-
Alamycin LA 200 mg/ml Solution for Injection for Cattle, Sheep and Pigs; Alamycin LA 300 Solution for Injection 300 mg/ml [Cattle, Pigs, Sheep]
Active substance: Oxytetracycline
Territory / Distribution category: UK POM-V
Authorisation holder: Norbrook Laboratories Limited
Change Category: Adverse reactions
Summary of change:
Section 4.6: The following adverse event associated with the frequency very rare has been change to: “hypersensitivity, allergic or anaphylactic type reactions may occur that in extreme cases may be fatal.”
-
Fly & Lice Spot On Insecticide 1% w/v Cutaneous Solution [Cattle, Sheep]
Active substance: Deltamethrin
Territory / Distribution category: UK POM-VPS
Authorisation holder: Zoetis UK Limited
Change Category: Adverse reactions
Summary of change:
Section 3.6: Application site reactions, including squamosis and pruritus have been very rarely seen in cattle during the 48 hours after treatment.
The frequency of adverse reactions is defined using the following convention:
- very rare (less than 1 animal in 10,000 animals treated, including isolated reports)
-
MS-H Vaccine eyedrops suspension [Chickens]
Active substance: Mycoplasma synoviae
Territory / Distribution category: GB POM-V
Authorisation holder: Pharmsure International Ltd
Change Category: Name change, Target species use; Contraindications, Special warnings
Summary of change:
Section 1 and 4.9: Change of the pharmaceutical form and route of administration from eye drops suspension and ocular use to oculonasal suspension and oculonasal use respectively.
Section 4.5: All birds in a flock/common housed group must be vaccinated at the same time.
Variations - Companion animal species
-
Simparica Trio Chewable Tablets for Dogs [Range]
Active substance: Moxidectin, Pyrantel, Sarolaner
Territory / Distribution category: NI POM-V
Authorisation holder: Zoetis Belgium
Change Category: Indictions for use
Summary of change:
Section 3.2: For reduction of the risk of infection with Dipylidium caninum via transmission by Ctenocephalides felis for one month after treatment. The effect is indirect due to product’s activity against the vector.
Section 4.2: Sarolaner reduces the risk of infection with Dipylidium caninum via transmission by Ctenocephalides felis by killing the fleas before disease transmission occurs.
SPCs available from the EU Union Product Database
February 2025
New Authorisations
-
Beaphar Flea 11.4 mg Tablets for Cats; Beaphar Flea 11.4 mg Tablets for Small Dogs; Beaphar Flea 57 mg Tablets for Medium & Large Dogs
Active substance: Nitenpyram
Territory / Distribution category: GB AVM-GSL
Authorisation holder: Elanco Europe Ltd
Link to SPC Medium and Large Dogs
-
Lozenord 5 mg/ml Solution for Injection for Dogs and Cats
Active substance: Meloxicam
Territory / Distribution category: NI POM-V
Authorisation holder: Accord Healthcare B.V
Variations - food producing species
-
Avishield ND, Lyophilisate for Oculonasal Suspension/Use in Drinking Water, for Chickens and Turkeys
Active substance: Newcastle disease virus
Territory / Distribution category: NI POM-V
Authorisation holder: Genera Inc.
Change Category: Contraindications, Special warnings
Summary of change:
Section 4.7: Deletion of the safety warning not to use the vaccine during lay and from 4 weeks before the onset of lay in chickens but not in turkeys as follows;
Laying birds
Chickens: Vaccination during lay is safe when it is performed in laying chickens which are already immunised against Newcastle disease virus by vaccination.
Turkeys:
Do not use in birds in lay and within 4 weeks before the start of the laying period.
-
Bovilis Nasalgen-C Nasal Spray, Lyophilisate and Solvent for Suspension for Cattle
Active substance: Bovine coronavirus
Territory / Distribution category: GB POM-V
Authorisation holder: MSD Animal Health UK Limited
Change Category: Contraindications, Special warnings
Summary of change:
Section 3.7: Deletion of the safety warning not to use the vaccine during pregnancy as follows; Pregnancy and lactation: Can be used during pregnancy.
-
MS-H Vaccine eyedrops suspension [Chickens]
Active substance: Mycoplasma synoviae
Territory / Distribution category: NI POM-V
Authorisation holder: Pharmsure International Ltd
Change Category: Contraindications, Special warnings
Summary of change:
Section 3.5: Revision of special precautions for safe use in the target species by strengthening the warnings and the description of flock testing.
Link to SPC to follow
Variations - Companion animal species
-
Drontal Plus Flavour Tablets for Dogs
Active substance: Febantel; Praziquantel; Pyrantel Embonate
Territory / Distribution category: UK NFA-VPS
Authorisation holder: Vetoquinol UK Limited
Change Category: Name Change
Summary of change:
Change in name to Johnson’s Wormer Plus 150/144/50mg Tablets for Dogs & Puppies.
-
Stronghold Plus 15 mg/2.5 mg Spot-on Solution for Cats ≤2.5 kg; Stronghold Plus 30 mg/5 mg Spot-on Solution for Cats >2.5–5 kg; Stronghold Plus 60 mg/10 mg Spot-on Solution for Cats >5 – 10 kg
Active substance: Sarolaner Selamectin
Territory / Distribution category: GB POM-V
Authorisation holder: Zoetis UK Limited
Change Category: Target species use; Contraindications, Special warnings
Summary of change:
Section 4.2: Addition of 'Treatment of notoedric mange (Notoedres cati)' to the indications for use.
Section 4.4: Added 'The efficacy of the veterinary medicinal product has not been established in cats with severe clinical signs of notoedric mange'.
-
WORMclear Praziquantel 20 mg Spot-on Solution for Cats
Active substance: Praziquantel
Territory / Distribution category: UK AVM-GSL
Authorisation holder: Vetoquinol UK Limited
Change Category: Contraindications, Special warnings; Adverse reactions
Summary of change:
Section 4.5: Added ‘Laboratory studies in rabbits and rats with the excipient N-methyl pyrrolidone have shown evidence of foetotoxic effects. The veterinary medicinal product should not be administered by pregnant women. Personal protective equipment consisting of gloves should be worn when handling the product’
Section 4.6: Added ‘Occasionally a transient local reaction, such as scurf, mild exudation, alopecia, scab, erythema and pruritus may be observed at the application site following treatment. The product is bitter tasting and transient salivation may occasionally occur if the cat licks the application site immediately after treatment.
Section 4.7: Added ‘The safety of the product has not been established in cats during pregnancy, lactation or in animals intended for breeding.’
-
Posatex ear drops suspension for dogs
Active substance: Mometasone Furoate Monohydrate; Orbifloxacin; Posaconazole
Territory / Distribution category: GB POM-V
Authorisation holder: MSD Animal Health UK Limited
Change Category: Target species use; Packaging changes
Summary of change:
Section 3.9: Added ‘The inherent viscosity will result in a reduced delivery volume compared to the fill volume.’
Section 5.4: Pack sizes updated according to reduced delivery volume compared to the fill volume.
-
Vidalta 10 mg / 15 mg Prolonged-release Tablets for Cats
Active substance: Carbimazole
Territory / Distribution category: GB & NI POM-V
Authorisation holder: MSD Animal Health UK Limited
Change Category: Adverse reactions
Summary of change:
Section 3.6: There has been a change to the frequency of the adverse events; ‘ataxia’ and ‘pyrexia’ from ‘Very rare’ to ‘Rare’.